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A Feasibility Study On 3D Printed Biopsy Needles: Pronged Tips And INternal Features Affect On Tissue Yield

A Feasibility Study On 3D Printed Biopsy Needles: Pronged Tips And INternal Features Affect On Tissue Yield

Primary Author: Anika VanDeen

Faculty Sponsor: Roland Chen

 

Primary College/Unit: Voiland College of Engineering and Architecture

Category: Engineering and Environmental Science

Campus: Pullman

 

Abstract:

 

Principal Topic

Cancer is an ever-prevalent disease accounting for a large portion of medical services. With an aging world population, it is imperative to have efficient and non-invasive diagnostics. Biopsy methods such as core needle biopsy (CNB) and fine needle aspiration (FNA) are some of the most common practices used to garner an accurate diagnosis.

Methods

This study explores the feasibility of using 3D printing to fabricate biopsy needles with advanced designs that cannot be manufactured using traditional methods. We focus on enhancing the needle tip geometry as well as the addition of an internal feature to help improve tissue yield amounts. Four needle designs were tested, two with a bevel shaped tip, and two with a five-pronged tip, both with and without the internal feature.

 

Results/Implications

Average total yield for the beveled needle with no feature (n=10), was 3.217 mg (s=0.9104), and for the beveled needle with feature, five-pronged needle without feature, and the five-pronged needle with feature (n=22), measured 8.31 mg (s=3.07 mg), 16.16 mg (s=12.21), and 26.34 mg (s=12.94), respectively. There is a statistical difference in yield tissue amounts between the five-prong needle with and without feature (p=0.01). The pronged-tip design with the internal feature is shown to have a significant effect on tissue sampling efficiency. The 3D printed needles do create higher insertion force than that of the stainless-steel needles. This study demonstrates the feasibility of using 3D printing to fabricate biopsy needles with enhanced tissue sampling efficiency.

 

Modeling the Impact of Staff to Patient Ratios on MRSA Acquisition in an Intensive Care Unit

Modeling the Impact of Staff to Patient Ratios on MRSA Acquisition in an Intensive Care Unit

Primary Author: Stephanie Sikavitsas Johnson

Faculty Sponsor: Eric Lofgren

 

Primary College/Unit: College of Veterinary Medicine

Category: Medical and Life Sciences

Campus: Pullman

 

Abstract:

 

Staff-to-Patient ratios in hospitals impact several hospital acquired infections (HAIs). Intuitively, increasing the number of nurses and doctors in an intensive care unit (ICU) should impact rates of HAI transmission by reducing the number of patients per provider, allowing less patient-patient interaction. Designing a study to determine how different staffing ratios would affect HAIs is difficult to in person because of lots of different factors that make each hospital and unit unique. Mathematical modeling can be used instead to simulate how staffing ratios affect methicillin-resistant S. aureus (MRSA) being acquired in a 15-bed ICU.

 

We varied the number of doctors in the ICU from one to three. For each doctor scenario, the nurse -patient ratio was 1:1, 1:2.5, 1:3. And 1:5. We ran each model 1000 times, with each time simulating 1 year in the ICU. The outcome was the mean number of MRSA acquisitions in one year for each of the 12 models. Our baseline model we compared everything to was the single doctor, 1:3 nurse-patient ratio model.

 

Adding more doctors slightly decreased the number of acquisitions, with the steeper decline going from one doctor to two. Going from a 1:3 nursing ratio to 1:1 ratio decreased MRSA acquisition by 64%. Increasing to a 1:5 ratio raised acquisitions 21.5%. These results suggest reduction in provider contact may have an impact on HAI rates. Appropriate staffing should be considered in infection control guidelines, and the cost of staffing be weighed against its impact on infection prevention.